Deposition of Organic-Inorganic Nanocomposite Coatings for Biomedical Applications

Polymethylmethacrylate (PMMA) is a material of choice for many biomedical coating applications. However, such applications are limited due to the toxicity traditional solvents used solution processing PMMA coatings and composites. This problem addressed using an isopropanol-water co-solvent, which allows dissolution high molecular mass fabrication by dip-coating method from concentrated solutions. The use co-solvent offers versatile strategy solubilization deposition, despite insolubility in water isopropanol. Composite obtained, containing hydroxyapatite, silver oxide, zinc micron size silica nanosilica. Such promising manufacturing implants with enhanced biocompatibility, bioactivity antimicrobial properties biosensors. Ibuprofen, tetracycline amoxicillin as model drugs PMMA-drug composite drug delivery. microstructure composition analyzed. this investigation provides platform various